ANTI-CEACAM5 ANTIBODIES AND USES THEREOF

ANTI-CEACAM5 ANTIBODIES AND USES THEREOF

The present application discloses antibodies which bind human andMacaca fascicularisCEACAM5 proteins, as well as isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies. The application also discloses immunoconjugates comprising said antibodies conjugated or lin...

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Bibliographische Detailangaben
Hauptverfasser: Cameron, Béatrice, Dabdoubi, Tarik, Decary, Stéphanie, Blanche, Francis, Rak, Alexey, Berne, Pierre-François, Bouchard, Hervé, Ferrari, Paul
Format: Patent
Sprache:hrv ; eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present application discloses antibodies which bind human andMacaca fascicularisCEACAM5 proteins, as well as isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibodies. The application also discloses immunoconjugates comprising said antibodies conjugated or linked to a growth-inhibitory agent, and to pharmaceutical compositions comprising antibodies, or immunoconjugates of the disclosure. The antibodies or immunoconjugates described herein are used for the treatment of cancer or for diagnostic purposes.