COMBINATION THERAPY WITH AN ANTITUMOR ALKALOID

The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhib...

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Bibliographische Detailangaben
Hauptverfasser: García Fernández, Luis Francisco, Guillén Navarro, María José, Santamaría Núñez, Gema, Moneo Ocaña, Victoria, Galmarini, Carlos María, Avilés Marín, Pablo Manuel
Format: Patent
Sprache:hrv ; eng
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Zusammenfassung:The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.