THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS

The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...

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Bibliographische Detailangaben
Hauptverfasser:	Palomo Nicolau, Francisco, Pérez De La Cruz Moreno, María Ángeles, Rodríguez Salguero, Beatriz, Sánchez-Quesada, Jorge, Martínez Montero, Olga, López Ogalla, Javier, Medina Padilla, Miguel, Fuertes Huerta, Ana, De Cristobal Blanco, Javier, Herrero Santos, Susana, Domínguez Correa, Juan Manuel
Format:	Patent
Sprache:	hrv ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.