COMPOSITION FOR CARTILAGINOUS TISSUE REPAIR AND A PRODUCTION METHOD THEREFOR

The present invention relates to a composition for cartilaginous tissue repair and a production method thereof. To this end, the present invention comprises the steps of: (a) dissolving freeze-dried fibrinogen in an aprotinin solution; (b) dissolving freeze-dried thrombin in a stabilizing solution;...

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Bibliographische Detailangaben
Hauptverfasser: Yu, Ji-Chul, Kim, Hyun-Jo, Yeo, Se-Ken, Park, Hyun-Shin, Lee, Sae-Bom, Park, Ju-Hee, Kim, Seok-Jung, Jang, Cheong-Ho, Jang, Jae-Deog
Format: Patent
Sprache:hrv ; eng
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Zusammenfassung:The present invention relates to a composition for cartilaginous tissue repair and a production method thereof. To this end, the present invention comprises the steps of: (a) dissolving freeze-dried fibrinogen in an aprotinin solution; (b) dissolving freeze-dried thrombin in a stabilizing solution; (c) mixing an enriched collagen solution with thrombin and the stabilizing solution; and installing the fibrinogen solution (a) to one side of a dual kit and the solution (c) containing the collagen to the other side, and then mixing (a) and (c), and injecting into damaged cartilaginous tissue. The present invention provides effective regeneration of damaged cartilaginous tissue by a transplantable form composed of biomaterials such as collagen and fibrinogen, and this method reduces burden of surgery, and rapid and effective regeneration and restoration of cartilage defect region is induced. The present invention provides improved quality and reliability of the product that imparts good image to the patients.