PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.

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Bibliographische Detailangaben
Hauptverfasser: DEMATTEI, JOHN, RYAN, MICHAEL P, BOTFIELD, MARTYN C, KRUEGER, BRIAN R, ZLOKARNIK, GREGOR, VAN GOOR, FREDERICK F, LOOKER, ADAM R, NEUBERT-LANGILLE, BOBBIANNA, TRUDEAU, MARTIN, GROOTENHUIS, PETER D. J, ROEPER, STEFANIE, YAP, DAHRIKA MILFRED LAO
Format: Patent
Sprache:hrv ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.