SUBSTITUTED PYRAZOLO-PYRIDINES, COMPOSITIONS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE

Produkt slijedece formule (I): naznacen time daAr-1-A jekod kojeg se X2 odabire iz N, C-CH3, CF I CH. A se odabire iz fenila, pirazola i izoksazolila, po potrebi supstituiranog jednim ili vise supstituenata odabranih iz halogena; (C1-C12)alkila; (C6-C14)arila; (C1-C13) heteroarila koji ima 1 do4 heteroatoma; (C3-C12)cikloalkila; (C1-C13)heterociklila koji ima 1 to 4 heteroatoma; (C2-C12)alkilena; (C2-C12)alkinila; OH; O-(C1-C12) alkil; O-(C2-C12)alkilen; O-(C6-C14)aril; O-(C1-C13)heteroaril koji ima 1 to 4 heteroatoma; NH2; NH-(C1-C12)alkila; NH-(C6-C14)arila; NH-(C1-C13)heteroarila; N-(C1-C12)alkil-(C1-C12)alkial; SH; S-(C1-C12)alkila; S-(C6-C14)arila; S(O2)H; S(O2)-(C1-C12)alkila; S(O2)-(C6-C14)arila; SO3H; SO3-(C1-C12)alkil; SO3-(C6-C14)arila; CHO; C(O)-(C1-C12)alkila; C(O)-(C6-C14)arila; C(O)OH; C(O)O-(C1-C12)alkila; C(O)O-(C6-C14)arila; OC(O)-(C1-C12)alkila; OC(O)-(C6-C14)arila; C(O)NH2; C(O)NH-(C1-C12)alkila; C(O)NH-(C6-C14)arila; NHCHO; NHC(O)-(C1-C12)alkila;NHC(O)-(C6-C14)arila; NH-(C3-C12)cikloalkila; NH-(C1-C13) heterociklila koji ima 1 to 4 heteroatoma; CONH-(C1-C13)heterociklila koji ima 1 to 4 heteroatoma; CO-(C1-C13)heteroarila koji ima 1to 4 heteroatoma; CO-(C1-C13) heterociklila koji ima 1 to 4 heteroatoma; NHCO-(C1-C13)heteroarila koji ima 1 to4 heteroatoma; NHCO-(C1-C13)heterociklila koji ima 1 to 4 heteroatoma; NHCONH-(C1-C12)alkila. L se odabire iz skupine koja se sastoji iz: NH-SO2, -NH-CO-NH; Jedan od X, Y I Z odabire se iz N i NO, a dva drugi iz Z, Y i X su C(R5) i C(R6) Patent sadrzi jos 15 patentnih zahtjeva. The disclosure relates to substituted pyrazolo-pyridines, compositions containing them, methods for the production thereof, and to their use as medicaments, in particular, as anticancer agents.