5-PHENYL-4-METHYL-THIAZOL-2-YL-AMINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3 KINASE ENZYMES (PI3) FOR THE TREATMENT OF INFLAMMATORY AIRWAY DISEASES

5-PHENYL-4-METHYL-THIAZOL-2-YL-AMINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3 KINASE ENZYMES (PI3) FOR THE TREATMENT OF INFLAMMATORY AIRWAY DISEASES

Spoj, naznačen ti me, da je 1-[2-(2-etil-2H-tetrazol-5-il)-etil]-3-[5-(3-fluoro-4-metansulfonil-fenil)-4-metil-tiazol-2-il]-urea u slobodnom obliku ili u obliku soli. Patent sadrži još 5 patentnih zahtjeva. Compounds of Formula I: in free or salt form, wherein Ra, Rb, R2, R3, R4 and R5 have the mean...

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Bibliographische Detailangaben
Hauptverfasser: G. C. BLOOMFIELD, JUDY FOX HAYLER, IAN BRUCE, D. M. LE GRAND, C. LEBLANC, CLIVE MCCARTHY
Format: Patent
Sprache:hrv ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Spoj, naznačen ti me, da je 1-[2-(2-etil-2H-tetrazol-5-il)-etil]-3-[5-(3-fluoro-4-metansulfonil-fenil)-4-metil-tiazol-2-il]-urea u slobodnom obliku ili u obliku soli. Patent sadrži još 5 patentnih zahtjeva. Compounds of Formula I: in free or salt form, wherein Ra, Rb, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.