PHOTOSENSITISER AND METHOD FOR PRODUCTION THEREOF

Fotosenzitizer koji sadrži klor kao sol s alkalijskim metalom, naznačen time, da je klor sastavljen od klora c6 (13-karboksi-17-[2-karboksietil]-15-karboksimetil-17,18-trans-dihidro-3-vinil-8-etil-2,7,12,18-tetrametil-porfirin) što čini 80 - 90%, purpurin 5 (13-karboksi-17-[2-karboksietil]-15-formil...

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Hauptverfasser:	IGOR DMITRIEVICH ZALEVSKY, VALERY ALEXEEVICH PRIVALOV, ALEXANDR TIKHONOVICH GRADJUSHKO, JURY VIKTOROVICH KEMOV, ANDREI VALENTINOVICH IVANOV, ALEXANDR VLADIMIROVICH LAPPA, VLADIMIR ALEXANDROVICH ROMANOV, NATALIYA PETROVNA NEUGODOVA, ANDREI VALENTINOVICH RESHETNIKOV, OLGA YURIEVNA ABAKUMOVA, ARTASHES VACHEEVICH KARMENYAN, VLADIMIR PETROVICH LAPTEV
Format:	Patent
Sprache:	hrv ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Fotosenzitizer koji sadrži klor kao sol s alkalijskim metalom, naznačen time, da je klor sastavljen od klora c6 (13-karboksi-17-[2-karboksietil]-15-karboksimetil-17,18-trans-dihidro-3-vinil-8-etil-2,7,12,18-tetrametil-porfirin) što čini 80 - 90%, purpurin 5 (13-karboksi-17-[2-karboksietil]-15-formil-17,18-trans-dihidro-3-vinil-8-etil-2,7,12,18- tetrametilporfirin) što čini 5 - 20%, purpurin 18 - klor p6 (13-karboksi-17-[2-karboksietil]-15-karboksi-17,18-trans-dihidro-3-vinil-8-etil-2,7,12,18-tetrametilporfirin) što čini ostatak, tako da navedene komponente oblikuju sastav. Patent sadrži još 7 patentnih zahtjeva. The invention relates to medicine and concerns a photosensitiser for detecting and curing tumors. The inventive photosensitiser is embodied in the form of a composition containing chlorine in the form of salt and alkali metals. 80-90% of chlorine e6, 5-20% of purpurin 5 and the rest being purpurin 18 are used as chlorine. Said photosensitiser is produced by extracting Spirulina biomass with the aid of aceton. Afterwards said biomass is exposed to acid treatment, neutralisation, hydrolysis, extraction of feoforbide alpha , dissolution in aceton, addition of a strong base, neutralisation and reprecipitation of chlorine 6.