COMPOUNDS WITH A SULFONAMIDE GROUP AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THESE COMPOUNDS

Spoj koji kao predlijek i/ili nosač omogućava unošenje djelatnog sastojka u eritrocite i/ili vezivanje djelatnog sastojka za eritrocite, koji je karakteriziran time da njegovo unošenje u eritrocite i/ili vezivanje za eritrocite omogućava skupina-SO2NR1R2u kojoj skupine R1 i R2 neovisno jedna o drugoj predstavljaju atom vodika, acil radikal, alkil radikal, cikloalkil radikal, aril radikal, cijano skupinu ili hidroksi skupinu, a rečeni je spoj naznačen time da predstavlja predlijek slijedeće strukture: djelatni sastojak - prostorni razdjelitelj -SO2NR1R2s tim da djelatni sastojak u svojoj slobodnoj formi posjeduje funkcionalnu skupinu. Patent sadrži još 24 patentna zahtjeva. The invention relates to compounds which, acting as a prodrug and/or support, enable an active agent to be taken up by the erythrocytes and/or an active agent to bind to the erythrocytes. The uptake of these compounds by and/or the binding thereof to the erythrocytes is made possible by a group of formula -SO2NR1R2, wherein R1 and R2, independently of each other, mean a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an aryl group, a cyano group or a hydroxy group. The inventive prodrugs enable active agents such as endogenic substances, natural substances and synthetic substances with therapeutically useful properties which have a high "first path" effect, to be administered orally effectively or significantly improve the oral activity thereof.