ANTICUERPOS DE P-CADERINA

La presente invención se refiere a anticuerpos y a porciones de unión a antígeno de los mismos que se unen a P-caderina. The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The i...

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Bibliographische Detailangaben
Hauptverfasser:	MELANIE BOYLE, TODD LEE VANARSDALE, RICHARD DAVID HEAD, RICHARD ALLEN MAZZARELLA, RALPH RAYMOND MINTER, MAUREEN JERI BOURNER, BARRETT RICHARD THIELE, DAVID WILLIAM GRIGGS, GERALD FRIES CASPERSON, CRISTOPHER TODD BAUER, WILLIAM DEAN JOY, MARK ALLEN MOFFAT
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
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Beschreibung
Zusammenfassung:	La presente invención se refiere a anticuerpos y a porciones de unión a antígeno de los mismos que se unen a P-caderina. The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.