DERIVADOS DE BENCENOSULFONAMIDA

LA PRESENTE INVENCION SE REFIERE A UN DERIVADO DE BENCENOSULFONAMIDA QUE ES UTIL COMO INGRDIENTE ACTIVO DE PREPARACIONES FARMACEUTICAS. The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzene...

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Hauptverfasser: MAKIKO MARUMO, KEVIN BACON, KEIKO FUKUSHIMA, TOSHIYA MORIWAKI, NAOKI TSUNO, KLAUS URBAHNS, NORIKO NUNAMI, YINGFU LI, HIROMI SUGIMOTO, NAGAHIRO YOSHIDA, KENTARO HASHIMOTO
Format: Patent
Sprache:spa
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Zusammenfassung:LA PRESENTE INVENCION SE REFIERE A UN DERIVADO DE BENCENOSULFONAMIDA QUE ES UTIL COMO INGRDIENTE ACTIVO DE PREPARACIONES FARMACEUTICAS. The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of disease associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. wherein X represents O or S; R 4 represents the other substituents are as defined in claim 1.