New amines, their use and preparation

Novel 3,3-diphenylpropylamines of formula I wherein R signifies hydrogen or methyl, R , R and R independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphanoyl or halogen, and X represents a tertiary amino group -NR ,R , wherein R and R signify non-aromatic hydrocarbyl groups, which...

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Hauptverfasser: BENGT AKE SPARF, NILS AKE JONSSON, MIKIVER LEMBIT, LISBET NILVEBRANT, PINCHAS MOSES, GUNILLA GLAS
Format: Patent
Sprache:eng
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Zusammenfassung:Novel 3,3-diphenylpropylamines of formula I wherein R signifies hydrogen or methyl, R , R and R independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphanoyl or halogen, and X represents a tertiary amino group -NR ,R , wherein R and R signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and which may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers, their use as drugs, especially as anticholinergic agents, their use for preparing an anticholinergic drug, pharmaceutical compositions containing the novel amines, and methods for preparing the same.