OXIDIZED ANALOGS OF 17 BETA-N-MONOSUBSTITUTED CARBAMOYL-4-AZA 5ALPHA-ANDROST-1-EN-3-ONES

The compounds of formula (I) wherein R is selected from hydrogen, methyl or ethyl, and R is C1-12 straight or branched chain alkyl wherein one of the hydrogens is substituted by hydroxy, carboxylic acid or C1-4 alkyl ester, and A is -CH2-CH2 or -CH=CH-, and pharmaceutical formulations of the above c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	RASMUSSON, GARY H, CARLIN, JOSEPHINE R, VANDENHEUVEL, W.J.A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The compounds of formula (I) wherein R is selected from hydrogen, methyl or ethyl, and R is C1-12 straight or branched chain alkyl wherein one of the hydrogens is substituted by hydroxy, carboxylic acid or C1-4 alkyl ester, and A is -CH2-CH2 or -CH=CH-, and pharmaceutical formulations of the above compounds are active as testosterone 5 alpha -reductase inhibitors and thus are useful for treatment of acne, seborrhea, female hirsutism or benign prostatic hypertrophy.