BICYCLIC COMPOUNDS USEFUL FOR TREATING DISEASES CAUSED BY RETROVIRUSES

Methods for preventing or treating retroviral infection not HIV and/or for preventing, inhibiting or treating a disease caused by the retroviral infection include contacting a cell with compound (I) wherein: means a pyridazine, pyrimidine or pyrazine group, R independently represent a hydrogen atom,...

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Hauptverfasser: NAJMAN, ROMAIN R, CAMPOS, NOELIE N, SCHERRER, DIDIER D, GARCEL, AUDE A, TAZI, JAMAL J, MAHUTEAU-BETZER, FLORENCE F
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Methods for preventing or treating retroviral infection not HIV and/or for preventing, inhibiting or treating a disease caused by the retroviral infection include contacting a cell with compound (I) wherein: means a pyridazine, pyrimidine or pyrazine group, R independently represent a hydrogen atom, halogen atom or group chosen among a -CN, hydroxyl, -COOR1, (C1-C3)fluoroalkyl, (C1-C3)fluoroalkoxy, -NO2, -NR1R2, (C1-C4)alkoxy, phenoxy and (C1-C3)alkyl group, the alkyl being optionally mono-substituted by hydroxyl group, n is 1, 2 or 3, n′ is 1 or 2, R′ is a hydrogen atom, halogen atom or group chosen among (C1-C3)alkyl group, hydroxyl group, -COOR1 group, -NO2 group, -NR1R2 group, morpholinyl or morpholino group, N-methylpiperazinyl group, (C1-C3)fluoroalkyl group, (C1-C4)alkoxy group and -CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C.