ARYL AND HETEROARYL FUSED LACTAMS

ARYL AND HETEROARYL FUSED LACTAMS

This invention relates to compounds of general formula (I) in which R 1 , R 2 , U, V, L, M, R 5 , m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MCALPINE, INDRAWAN JAMES IJ, NINKOVIC, SACHA S, EDWARDS, MARTIN PAUL MP, KUMPF, ROBERT ARNOLD RA, RUI, EUGENE YUANJIN EY, WYTHES, MARTIN JAMES MJ, ZEHNDER, LUKE RAYMOND LR, SUTTON, SCOTT CHANNING SC, KUNG, PEI-PEI P-P, TATLOCK, JOHN HOWARD JH
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention relates to compounds of general formula (I) in which R 1 , R 2 , U, V, L, M, R 5 , m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.