ENZYMATIC OMEGA-OXIDATION AND OMEGA-AMINATION OF FATTY ACIDS

Oxidizing fatty acid or its ester (I), comprises (a) contacting (I) with cytochrome P450-monooxygenase of cytochrome P153 (CYP153) family in presence of molecular oxygen and NADPH. Oxidizing fatty acid or its ester of formula (H 3C-(CH 2) n-COOR) (I), comprises (a) contacting (I) with cytochrome P45...

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Hauptverfasser: HAUBERG, MICHAELA, PFEFFER, JAN CHRISTOPH, HENNEMANN, HANS-GEORG, HGER, HARALD, WESSEL, MIRJA, HAAS, THOMAS, SCHAFFER, STEFFEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Oxidizing fatty acid or its ester (I), comprises (a) contacting (I) with cytochrome P450-monooxygenase of cytochrome P153 (CYP153) family in presence of molecular oxygen and NADPH. Oxidizing fatty acid or its ester of formula (H 3C-(CH 2) n-COOR) (I), comprises (a) contacting (I) with cytochrome P450-monooxygenase of cytochrome P153 (CYP153) family in presence of molecular oxygen and NADPH. R : H, CH 3, ethyl, propyl or butyl; and n : 0-30, preferably 6-24. An independent claim is also included for a whole-cell catalyst expressing a recombinant cytochrome P450 monooxygenase, a recombinant alcohol dehydrogenase, a recombinant transaminase and optionally at least one recombinant enzyme, preferably alanine dehydrogenase, ferredoxin or ferredoxin reductase.