INDOLE AND INDAZOLE COMPOUNDS THAT ACTIVATE AMPK AMPK

The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, o...

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Hauptverfasser: BHATTACHARYA, SAMIT KUMAR SK, SMITH, AARON CHRISTOPHER AC, FILIPSKI, KEVIN JAMES KJ, CAMERON, KIMBERLY OKEEFE KO, EDMONDS, DAVID JAMES DJ, FERNANDO, DILINIE PRASADHINI DP, KUNG, DANIEL WEI-SHUNG DW-S, EBNER, DAVID CHRISTOPHER DC, LEE, ESTHER CHENG YIN ECY, DOWLING, MATTHEW SCOTT MS, TU, MEIHUA MIKE MM
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.