3D IN VITRO BI-PHASIC CARTILAGE-BONE CONSTRUCT 3D

The present invention is directed to a 3D in vitro bi-phasic cartilage-bone organoid comprising: a) a layer of artificial cartilage tissue; and b) a layer of artificial bone tissue, wherein the artificial bone tissue comprises a structure-giving scaffold and a bone marrow structure; wherein the laye...

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Bibliographische Detailangaben
Hauptverfasser:	LAUSTER, ROLAND R, MARX, UWE U, FATEHI-VARKANI, SHIRIN S, ROSOWSKI, MARK M
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is directed to a 3D in vitro bi-phasic cartilage-bone organoid comprising: a) a layer of artificial cartilage tissue; and b) a layer of artificial bone tissue, wherein the artificial bone tissue comprises a structure-giving scaffold and a bone marrow structure; wherein the layer of artificial cartilage tissue contacts at least one surface of the layer of artificial bone tissue, as well as to uses and a method of production thereof.