PHARMACEUTICAL COMPOSITION OF MICROSPHERES FOR PREVENTING DIABETIC FOOT AMPUTATION

The present invention relates to a pharmaceutical composition that comprises polymeric microspheres containing epidermal growth factor (EGF) for the application, by the parenteral route, into the lower limbs of diabetic patients with cutaneous chronic ischemic ulcerative wounds. The pharmaceutical c...

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Hauptverfasser: BLAS YAMIR BETANCOURT RODRIGUEZ BY, JOSE ANGEL RAMON HERNANDEZ JA, JORGE AMADOR BERLANGA ACOSTA JA, VIVIAN MARIA SAEZ MARTINEZ VM, ROLANDO PAEZ MEIRELES R
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to a pharmaceutical composition that comprises polymeric microspheres containing epidermal growth factor (EGF) for the application, by the parenteral route, into the lower limbs of diabetic patients with cutaneous chronic ischemic ulcerative wounds. The pharmaceutical composition described herein, in contrast with the state of the art, is useful because reduce the administration frequency during the treatment and allows for the healing of the ulcerative wounds in a shorter time interval with respect to the injection of equivalent quantities of non-encapsulated EGF.