4-1BB BINDING MOLECULES 4-1BB

The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceuti...

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Hauptverfasser: RADHAKRISHNAN, Vinay V, BERGQVIST, Simon Paul SP, DOYONNAS, Regis R, ELLIOTT, Mark William MW, ZIEGEMEIER, Daisy Marie DM, ONADIPE, Adekunle Olatunbosun AO, TESAR, Michael M, ZULLEY, Moritz M, BAXI, Sangita M. SM, DUFIELD, Robert Lee RL, FISHER, Timothy Scott TS, YATES, Libbey Anne LA, KAMPERSCHROER, Cris C, LADETZKI-BAEHS, Kathrin K, LOVE, Victoria Alexandria VA, OLIPHANT, Theodore Lawrence TL, QIN, Wenning W, JEROME, Richard Michael RM, THOMAS, Kristin Elizabeth KE, SHARP, Leslie Lynne LL, AHRENS, Bianca B, JONES, Heather Laurence HL, ROHNER, Allison Karlyn AK
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.