PROCESS FOR THE PREPARATION OF MIXTURES OF TRIFLUOROACETYL GLATIRAMER ACETATE USING PURIFIED HYDROBROMIC ACID

PROCESS FOR THE PREPARATION OF MIXTURES OF TRIFLUOROACETYL GLATIRAMER ACETATE USING PURIFIED HYDROBROMIC ACID

The Subject invention provides an improved process for obtaining a mixture of polypeptides having nonuniform amino acid sequences, where each polypeptide consists essentially of alanine, glutamic acid, tyrosine and lysine where the resulting mixture of polypeptides comprises less than 0.3% brominate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: BEN-ZION DOLITZKY
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
METALLURGY
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
PEPTIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:The Subject invention provides an improved process for obtaining a mixture of polypeptides having nonuniform amino acid sequences, where each polypeptide consists essentially of alanine, glutamic acid, tyrosine and lysine where the resulting mixture of polypeptides comprises less than 0.3% brominated tyrosine and less than 1000 ppm metal ion impurities.