COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS RNA

Peptides are provided comprising the amino acid sequence of SEQ ID NO: 11 or a fragment, analog, mimetic, chemically-modified derivative, or salt thereof. These peptides are optionally conjugated to, or complexed with, a double-stranded RNA, and may be used to enhance delivery of the RNA to a target...

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Hauptverfasser: MOHAMMAD AHMADIAN, MICHAEL E. JR. HOUSTON, KUNYUAN CUI, SHUIH CHEN QUAY, LISHAN CHEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Peptides are provided comprising the amino acid sequence of SEQ ID NO: 11 or a fragment, analog, mimetic, chemically-modified derivative, or salt thereof. These peptides are optionally conjugated to, or complexed with, a double-stranded RNA, and may be used to enhance delivery of the RNA to a target cell.