HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological condit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HARRIS, ROY, LEONARD, III, PERRIN-NINKOVIC, SOPHIE, HUANG, DEHUA, RIGGS, JENNIFER R, MORTENSEN, DEBORAH, SUE, ALBERS, RONALD, J, SHEVLIN, GRAZIELLA, ISABEL, MEDEROS, MARIA MERCEDES, DELGADO, SCHWARZ, KIMBERLY, LYN, SAPIENZA, JOHN, JOSEPH, LEE, BRANDEN, G, TEHRANI, LIDA, RADNIA, PACKARD, GARRICK, K, PARNES, JASON, SIMON, PAPA, PATRICK, WILLIAM
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator HARRIS, ROY, LEONARD, III
PERRIN-NINKOVIC, SOPHIE
HUANG, DEHUA
RIGGS, JENNIFER R
MORTENSEN, DEBORAH, SUE
ALBERS, RONALD, J
SHEVLIN, GRAZIELLA, ISABEL
MEDEROS, MARIA MERCEDES, DELGADO
SCHWARZ, KIMBERLY, LYN
SAPIENZA, JOHN, JOSEPH
LEE, BRANDEN, G
TEHRANI, LIDA, RADNIA
PACKARD, GARRICK, K
PARNES, JASON, SIMON
PAPA, PATRICK, WILLIAM
description Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_HK1131145A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>HK1131145A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_HK1131145A13</originalsourceid><addsrcrecordid>eNrjZPDzcA1xDfJ3DIr0UXD29w3wD_VzCdaBMIM9Qzz9_YIVQjxcg1z93XQUHP1cFHxdQzz8XYIV_N0UQoJcHUN8Xf1CICrCPUM8eBhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvIe3oaGxoaGJqaOhMRFKAO2lLmA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH</title><source>esp@cenet</source><creator>HARRIS, ROY, LEONARD, III ; PERRIN-NINKOVIC, SOPHIE ; HUANG, DEHUA ; RIGGS, JENNIFER R ; MORTENSEN, DEBORAH, SUE ; ALBERS, RONALD, J ; SHEVLIN, GRAZIELLA, ISABEL ; MEDEROS, MARIA MERCEDES, DELGADO ; SCHWARZ, KIMBERLY, LYN ; SAPIENZA, JOHN, JOSEPH ; LEE, BRANDEN, G ; TEHRANI, LIDA, RADNIA ; PACKARD, GARRICK, K ; PARNES, JASON, SIMON ; PAPA, PATRICK, WILLIAM</creator><creatorcontrib>HARRIS, ROY, LEONARD, III ; PERRIN-NINKOVIC, SOPHIE ; HUANG, DEHUA ; RIGGS, JENNIFER R ; MORTENSEN, DEBORAH, SUE ; ALBERS, RONALD, J ; SHEVLIN, GRAZIELLA, ISABEL ; MEDEROS, MARIA MERCEDES, DELGADO ; SCHWARZ, KIMBERLY, LYN ; SAPIENZA, JOHN, JOSEPH ; LEE, BRANDEN, G ; TEHRANI, LIDA, RADNIA ; PACKARD, GARRICK, K ; PARNES, JASON, SIMON ; PAPA, PATRICK, WILLIAM</creatorcontrib><description>Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20100115&amp;DB=EPODOC&amp;CC=HK&amp;NR=1131145A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20100115&amp;DB=EPODOC&amp;CC=HK&amp;NR=1131145A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HARRIS, ROY, LEONARD, III</creatorcontrib><creatorcontrib>PERRIN-NINKOVIC, SOPHIE</creatorcontrib><creatorcontrib>HUANG, DEHUA</creatorcontrib><creatorcontrib>RIGGS, JENNIFER R</creatorcontrib><creatorcontrib>MORTENSEN, DEBORAH, SUE</creatorcontrib><creatorcontrib>ALBERS, RONALD, J</creatorcontrib><creatorcontrib>SHEVLIN, GRAZIELLA, ISABEL</creatorcontrib><creatorcontrib>MEDEROS, MARIA MERCEDES, DELGADO</creatorcontrib><creatorcontrib>SCHWARZ, KIMBERLY, LYN</creatorcontrib><creatorcontrib>SAPIENZA, JOHN, JOSEPH</creatorcontrib><creatorcontrib>LEE, BRANDEN, G</creatorcontrib><creatorcontrib>TEHRANI, LIDA, RADNIA</creatorcontrib><creatorcontrib>PACKARD, GARRICK, K</creatorcontrib><creatorcontrib>PARNES, JASON, SIMON</creatorcontrib><creatorcontrib>PAPA, PATRICK, WILLIAM</creatorcontrib><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH</title><description>Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPDzcA1xDfJ3DIr0UXD29w3wD_VzCdaBMIM9Qzz9_YIVQjxcg1z93XQUHP1cFHxdQzz8XYIV_N0UQoJcHUN8Xf1CICrCPUM8eBhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvIe3oaGxoaGJqaOhMRFKAO2lLmA</recordid><startdate>20100115</startdate><enddate>20100115</enddate><creator>HARRIS, ROY, LEONARD, III</creator><creator>PERRIN-NINKOVIC, SOPHIE</creator><creator>HUANG, DEHUA</creator><creator>RIGGS, JENNIFER R</creator><creator>MORTENSEN, DEBORAH, SUE</creator><creator>ALBERS, RONALD, J</creator><creator>SHEVLIN, GRAZIELLA, ISABEL</creator><creator>MEDEROS, MARIA MERCEDES, DELGADO</creator><creator>SCHWARZ, KIMBERLY, LYN</creator><creator>SAPIENZA, JOHN, JOSEPH</creator><creator>LEE, BRANDEN, G</creator><creator>TEHRANI, LIDA, RADNIA</creator><creator>PACKARD, GARRICK, K</creator><creator>PARNES, JASON, SIMON</creator><creator>PAPA, PATRICK, WILLIAM</creator><scope>EVB</scope></search><sort><creationdate>20100115</creationdate><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH</title><author>HARRIS, ROY, LEONARD, III ; PERRIN-NINKOVIC, SOPHIE ; HUANG, DEHUA ; RIGGS, JENNIFER R ; MORTENSEN, DEBORAH, SUE ; ALBERS, RONALD, J ; SHEVLIN, GRAZIELLA, ISABEL ; MEDEROS, MARIA MERCEDES, DELGADO ; SCHWARZ, KIMBERLY, LYN ; SAPIENZA, JOHN, JOSEPH ; LEE, BRANDEN, G ; TEHRANI, LIDA, RADNIA ; PACKARD, GARRICK, K ; PARNES, JASON, SIMON ; PAPA, PATRICK, WILLIAM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_HK1131145A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HARRIS, ROY, LEONARD, III</creatorcontrib><creatorcontrib>PERRIN-NINKOVIC, SOPHIE</creatorcontrib><creatorcontrib>HUANG, DEHUA</creatorcontrib><creatorcontrib>RIGGS, JENNIFER R</creatorcontrib><creatorcontrib>MORTENSEN, DEBORAH, SUE</creatorcontrib><creatorcontrib>ALBERS, RONALD, J</creatorcontrib><creatorcontrib>SHEVLIN, GRAZIELLA, ISABEL</creatorcontrib><creatorcontrib>MEDEROS, MARIA MERCEDES, DELGADO</creatorcontrib><creatorcontrib>SCHWARZ, KIMBERLY, LYN</creatorcontrib><creatorcontrib>SAPIENZA, JOHN, JOSEPH</creatorcontrib><creatorcontrib>LEE, BRANDEN, G</creatorcontrib><creatorcontrib>TEHRANI, LIDA, RADNIA</creatorcontrib><creatorcontrib>PACKARD, GARRICK, K</creatorcontrib><creatorcontrib>PARNES, JASON, SIMON</creatorcontrib><creatorcontrib>PAPA, PATRICK, WILLIAM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HARRIS, ROY, LEONARD, III</au><au>PERRIN-NINKOVIC, SOPHIE</au><au>HUANG, DEHUA</au><au>RIGGS, JENNIFER R</au><au>MORTENSEN, DEBORAH, SUE</au><au>ALBERS, RONALD, J</au><au>SHEVLIN, GRAZIELLA, ISABEL</au><au>MEDEROS, MARIA MERCEDES, DELGADO</au><au>SCHWARZ, KIMBERLY, LYN</au><au>SAPIENZA, JOHN, JOSEPH</au><au>LEE, BRANDEN, G</au><au>TEHRANI, LIDA, RADNIA</au><au>PACKARD, GARRICK, K</au><au>PARNES, JASON, SIMON</au><au>PAPA, PATRICK, WILLIAM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH</title><date>2010-01-15</date><risdate>2010</risdate><abstract>Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_HK1131145A1
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T07%3A27%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HARRIS,%20ROY,%20LEONARD,%20III&rft.date=2010-01-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EHK1131145A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true