HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological condit...

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Bibliographische Detailangaben
Hauptverfasser: HARRIS, ROY, LEONARD, III, PERRIN-NINKOVIC, SOPHIE, HUANG, DEHUA, RIGGS, JENNIFER R, MORTENSEN, DEBORAH, SUE, ALBERS, RONALD, J, SHEVLIN, GRAZIELLA, ISABEL, MEDEROS, MARIA MERCEDES, DELGADO, SCHWARZ, KIMBERLY, LYN, SAPIENZA, JOHN, JOSEPH, LEE, BRANDEN, G, TEHRANI, LIDA, RADNIA, PACKARD, GARRICK, K, PARNES, JASON, SIMON, PAPA, PATRICK, WILLIAM
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are Heteroaryl Compounds having the following structure: wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.