CELL-SELECTIVE DELIVERY SYSTEM

The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermor...

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Bibliographische Detailangaben
Hauptverfasser: SOOMETS, URSEL, POOGA, MARGUS, MEIKAS, ANNE, EL-ANDALOUSSI, SAMIR, ELMQUIST, ANNA, METSIS, MADIS, LUNDBERG, PONTUS, LANGEL, ULO, ZORKO, MATJAZ, KILK, KALLE, HAELLBRINK, MATTIAS, LINDGREN, MARIA, OESTENSSON, CLAES, GOERAN, JAERVER, PETER, KOGERMAN, PRIIT, GRAESLUND, ASTRID, SAAR, KUELLIKI, BUDIHNA, METKA, VALKNA, ANDREAS, ERIKSSON, GOERAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition.