METHOD FOR THE PREPARATION OF ESCITALOPRAM

A novel method is provided for the manufacture of escitalopram. The method comprises chromatographic separation of the enantiomers of citalopram or an intermediate in the production of citalopram using a chiral stationary phase such as Chiralpak™ AD or Chiralcel™ OD. Novel chiral intermediates for t...

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Bibliographische Detailangaben
Hauptverfasser:	COX, GEOFFEY, GEISER, FIONA, ASSENZA, SEBASTIAN, P, BECH SOMMER, MICHAEL, AHMADIAN, HALEH, LEE, JAMES, NIELSEN, OLE, NAIR, USHA, BROESEN, PETER, DAPREMONT, OLIVIER, HARIHARAN, SHANKAR, PETERSEN, HANS, SUTEU, CHRISTINA, PEDERSEN, HENRIK
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A novel method is provided for the manufacture of escitalopram. The method comprises chromatographic separation of the enantiomers of citalopram or an intermediate in the production of citalopram using a chiral stationary phase such as Chiralpak™ AD or Chiralcel™ OD. Novel chiral intermediates for the synthesis of Escitalopram made by said method are also provided.