Mercaptoacetylamide derivatives, a process for their preparation and their use

Mercaptoacetylamide derivatives, a process for their preparation and their use

This invention discloses and claims a series of mercaptoacetylamide derivatives of formula (I). Also disclosed and claimed are pharmaceutical compositions incorporating these compounds and processes for preparing said compounds. The use of said compounds for inhibition of the enzymes angiotensin con...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JACK ROGER KOEHL, BARBARA ANN ANDERSON, FLYNN, GARY, A, MANFRED GERKEN, HEINZ-WERNER KLEEMANN, WERNER SEIZ, SHUJAATH MEHDI, BERND JABLONKA, WOLFGANG LINZ, BERNHARD SEURING
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention discloses and claims a series of mercaptoacetylamide derivatives of formula (I). Also disclosed and claimed are pharmaceutical compositions incorporating these compounds and processes for preparing said compounds. The use of said compounds for inhibition of the enzymes angiotensin converting enzyme and neutral endopeptidase, and for the treatment of hypertension and congestive heart failure are also disclosed and claimed.