PARA-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS

The present invention relates to a class of compounds represented by Formula Ior a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphavbeta3 integrin.

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Bibliographische Detailangaben
Hauptverfasser:	THOMAS E. ROGERS, JAMES W. MALECHA, HELEN J. CHEN, BARBARA B. CHEN, STELLA S. YU, RICHARD A. HAAK, THOMAS D. PFENNING, JOSEPH G. RICO, PETER G. RUMINSKI, MARK A. RUSSEL, GLEN J. GESICKI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a class of compounds represented by Formula Ior a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphavbeta3 integrin.