Analogs of 15- deoxyspergualine process for their preparation and their use as immunosuppressive agents

15-deoxy-spergualin analogues of formula (I) and their addn. salts are new. X = (CH2)n; Y = (CH2)4; T = (CH2)2; A = a single bond, -CH2-, -CH2O-, -CH2NH-, -CH(OH)-, -CHF-, or -CH(OCH3)-; n = 6-8. Intermediate cpds. of formula (II) are also claimed. A has the values above or in addn. is CH(OCH2C6H5);...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	DERREPAS PHILIPPE, LEBRETON LUC, SAMRETH SOTH, DUTARTRE PATRICK, RENAUT PATRICE
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HAND TOOLS HUMAN NECESSITIES HYGIENE MANIPULATORS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PORTABLE POWER-DRIVEN TOOLS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TOOLS OR BENCH DEVICES NOT OTHERWISE PROVIDED FOR, FORFASTENING, CONNECTING, DISENGAGING OR HOLDING TRANSPORTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	15-deoxy-spergualin analogues of formula (I) and their addn. salts are new. X = (CH2)n; Y = (CH2)4; T = (CH2)2; A = a single bond, -CH2-, -CH2O-, -CH2NH-, -CH(OH)-, -CHF-, or -CH(OCH3)-; n = 6-8. Intermediate cpds. of formula (II) are also claimed. A has the values above or in addn. is CH(OCH2C6H5); R1, R2, R3 = amino-protective gps. of alkoxycarbonyl, benzyloxycarbonyl or benzyl type.