COMPUESTOS ORGANICOS

ESTA INVENCION COMPRENDE LOS COMPUESTOS DE PIPERIDINA 3,4-SUSTITUIDOS, PARA USO EN ANIMALES DE SANGRE CALIENTE CON FINES TERAPEUTICOS Y/O DE DIAGNOSTICO DE ENFERMEDADES O DESORDENES QUE DEPENDEN DE LA ACTIVIDAD DE LA RENINA. SE DESCRIBE EL COMPUESTO PARA FORMULACIONES FARMACEUTICAS, DE FORMULA GENERAL (I), QUE COMPRENDEN COMPUESTOS DE PIPERIDINA 3,4-SUSTITUIDOS Y METODO PARA SU MANUFACTURA. 3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4-substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula I, wherein the symbols have the meanings defined in the specification.