MONOCLONAL ANTIBODIES AGAINST GLYCOPROTEIN ASSOCIATED WITH TUMOR, PROCESSES FOR THEIR PREPARATION AND THEIR USE

The monoclonal antibody which is called MAb 436/15 and has the IgG3 isotype with a Kappa chain and reacts with a glycoprotein (antigen 1) which has a molecular weight (MW) exceeding 200 kDa under non-reducing conditions, the monoclonal antibody which is called MAb 494/32 and has the IgG1 isotype wit...

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Bibliographische Detailangaben
Hauptverfasser:	BOSSLET KLAUS, SEDLACEK HANS-HARALD, LUBEN GERHARD, KANZY JURGEN ERNST
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The monoclonal antibody which is called MAb 436/15 and has the IgG3 isotype with a Kappa chain and reacts with a glycoprotein (antigen 1) which has a molecular weight (MW) exceeding 200 kDa under non-reducing conditions, the monoclonal antibody which is called MAb 494/32 and has the IgG1 isotype with Kappa chain and reacts with a glycoprotein (antigen 2) which has an MW exceeding 200 kDa under non-reducing and under reducing conditions, and two monoclonal antibodies which are called MAbs 495/19 and 495/36 and have the IgG3 isotype with Kappa chain and react with a glycoprotein (antigen 3) which has an MW exceeding 200 kDa under non-reducing and under reducing conditions, and a process for the preparation thereof are described. These antibodies can be used for binding to the corresponding antigens on cells and tissues carrying these antigens, and therefore as diagnostic aids, therapeutic agents or as carriers for a pharmaceutical agent.