GR79640

Pyrazole derivatives of formula (I): wherein R min is hydrogen or methyl; Ar is pyridyl, thienyl, or optionally substituted phenyl; X is NH2, H, OH, halogen or C1-3 alkyl; and R is OH, OM, O-alk, NH2, NH-alk, N(alk)2 or N-alken-N-(alk)2; wherein alk is C1-5 alkyl; alken is (CH2)2 or (CH2)3 and M is...

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Hauptverfasser: J.R. BECK, R.P. GAJEWSKI, R.E. HACKLER
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creator J.R. BECK
R.P. GAJEWSKI
R.E. HACKLER
description Pyrazole derivatives of formula (I): wherein R min is hydrogen or methyl; Ar is pyridyl, thienyl, or optionally substituted phenyl; X is NH2, H, OH, halogen or C1-3 alkyl; and R is OH, OM, O-alk, NH2, NH-alk, N(alk)2 or N-alken-N-(alk)2; wherein alk is C1-5 alkyl; alken is (CH2)2 or (CH2)3 and M is a non-toxic cation; are useful in lowering blood urate levels in mammals.
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HACKLER</creatorcontrib><description>Pyrazole derivatives of formula (I): wherein R min is hydrogen or methyl; Ar is pyridyl, thienyl, or optionally substituted phenyl; X is NH2, H, OH, halogen or C1-3 alkyl; and R is OH, OM, O-alk, NH2, NH-alk, N(alk)2 or N-alken-N-(alk)2; wherein alk is C1-5 alkyl; alken is (CH2)2 or (CH2)3 and M is a non-toxic cation; are useful in lowering blood urate levels in mammals.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1984</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19841031&amp;DB=EPODOC&amp;CC=GR&amp;NR=79640B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19841031&amp;DB=EPODOC&amp;CC=GR&amp;NR=79640B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>J.R. BECK</creatorcontrib><creatorcontrib>R.P. GAJEWSKI</creatorcontrib><creatorcontrib>R.E. HACKLER</creatorcontrib><title>GR79640</title><description>Pyrazole derivatives of formula (I): wherein R min is hydrogen or methyl; Ar is pyridyl, thienyl, or optionally substituted phenyl; X is NH2, H, OH, halogen or C1-3 alkyl; and R is OH, OM, O-alk, NH2, NH-alk, N(alk)2 or N-alken-N-(alk)2; wherein alk is C1-5 alkyl; alken is (CH2)2 or (CH2)3 and M is a non-toxic cation; are useful in lowering blood urate levels in mammals.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1984</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZGB3DzK3NDMx4GFgTUvMKU7lhdLcDLJuriHOHrqpBfnxqcUFicmpeakl8VDVTsaE5AEgQhkP</recordid><startdate>19841031</startdate><enddate>19841031</enddate><creator>J.R. BECK</creator><creator>R.P. GAJEWSKI</creator><creator>R.E. HACKLER</creator><scope>EVB</scope></search><sort><creationdate>19841031</creationdate><title>GR79640</title><author>J.R. BECK ; R.P. GAJEWSKI ; R.E. HACKLER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_GR79640B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1984</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>J.R. BECK</creatorcontrib><creatorcontrib>R.P. GAJEWSKI</creatorcontrib><creatorcontrib>R.E. HACKLER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>J.R. BECK</au><au>R.P. GAJEWSKI</au><au>R.E. HACKLER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>GR79640</title><date>1984-10-31</date><risdate>1984</risdate><abstract>Pyrazole derivatives of formula (I): wherein R min is hydrogen or methyl; Ar is pyridyl, thienyl, or optionally substituted phenyl; X is NH2, H, OH, halogen or C1-3 alkyl; and R is OH, OM, O-alk, NH2, NH-alk, N(alk)2 or N-alken-N-(alk)2; wherein alk is C1-5 alkyl; alken is (CH2)2 or (CH2)3 and M is a non-toxic cation; are useful in lowering blood urate levels in mammals.</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title GR79640
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