GR77310
The object of the present invention are new pharmacologically active substituted imidazolylphenyl amidines as H2 receptor blocking agents, which inhibit gastric acid secretion and which are useful antiulcer agents of the following formulain which R, R, and R3, which may be the same or different, rep...
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Zusammenfassung: | The object of the present invention are new pharmacologically active substituted imidazolylphenyl amidines as H2 receptor blocking agents, which inhibit gastric acid secretion and which are useful antiulcer agents of the following formulain which R, R, and R3, which may be the same or different, represent a hydrogen atom or a lower alkyl group, and R2 represents a linear or branched alkyl, alkenyl or alkynyl group, a cyano group, a hydroxyl group, a substituted or unsubstituted cycloalkyl or cycloaliphatic alkyl group, a bicyclic group, an aralkyl or aryl group (optionally substituted by halogen, a methyl, methoxy or methylenedioxy group) or a substituted or unsubstituted heterocyclicalkyl or heterocyclic group which may also contain a further hetero atom; and non-toxic acid addition salts thereof. The processes for the preparation of the compounds of formula and their intermediates as well as pharmaceutical compositions containing them are also object of this invention. |
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