GR75255

The invention relates to new quinoxaline-1,4-derivatives of the general formula (I) and biologically acceptable salts thereof, (I) wherein Q is a hydrogen atom or a methyl group, R1 represents a hydrogen atom, a cyano, lower alkanoyl or nitro group or a halogen atom, R2 stands for cyano, lower alkanoyl, or a group of the general formula -COOR3, -CONR4R5 or -CO-NH-NR4R5, and R3 represents a hydrogen atom or a C1-18 alkyl, C6-12 aryl or C6-10 aryl-(C1-14 alkyl) group optionally substituted by a halogen atom or a hydroxy group, whereby the aromatic ring of the said groups may optionally contain 1-3 identical or different substituents selected from the group consisting of lower alkyl or alkoxy, amino, nitro, halogen and/or hydroxy, R4 is a hydrogen atom or a C1-18 alkyl, a lower alkenyl, a lower alkynyl, a lower cycloalkyl, C6-10 aryl, C6-10 aryl-(C1-4 alkyl) group optionally substituted by a halogen atom or a hydroxy group, whereby the aryl ring of the said groups may optionally contain 1-3 identical or different substituents selected from the group consisting of lower alkoxy, lower alkyl, amino, nitro, halogen and/or hydroxy substituents, a lower alkylcarbonyl, a lower alkylsulfonyl or a C6-10 arylsulfonyl group optionally substituted by an amino or a lower alkyl group; or a mono- or bicyclic heteroarylsulfonyl group, or R4 and R5 represent, together with the adjacent nitrogen atom, a 5 or 6 membered heterocyclic group optionally substituted by a further nitrogen or oxygen atom, with the proviso that if Q represents hydrogen and R2 stands for carboxy, R1 may denote only other than hydrogen. Moreover, the invention relates to a process for the preparation of the above compounds and fodder concentrates, fodder additives or fodders containing the said compounds. The new compounds of the general formula (I) possess weight-gain increasing and antibacterial effects and can be used to advantage in the animal husbandry.