Preparation and use of salts of 6,8-bis(amidiniumthio)octanoic acid
6,8-Bis(amidiniumthio)octanoic acid salts for formula CH2(SC(NH2)2X)-CH2-CH(SC(NH2)2Y)-CH 2-CH2-CH2-CH2-COOR (III) are new. R = H or 1-3C alkyl; X, Y = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is the use of (III) for the synthesis of racemic 6,8-dimerc...
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| creator | BEISSWENGER, THOMAS GEWALD, RAINER RAUTENBERG, STEPHAN OLBRICH, ALFRED DR KLENK, HERBERT BETHGE, HORST HUTHMACHER, KLAUS HUEBNER, FRANK MOELLER, ROLAND SATOR, GERHARD |
| description | 6,8-Bis(amidiniumthio)octanoic acid salts for formula CH2(SC(NH2)2X)-CH2-CH(SC(NH2)2Y)-CH 2-CH2-CH2-CH2-COOR (III) are new. R = H or 1-3C alkyl; X, Y = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is the use of (III) for the synthesis of racemic 6,8-dimercaptooctanoic acid, (+)-6,8-dihydrolipoic acid, (-)-6,8-dihydrolipoic acid, racemic alpha -lipoic acid, (+)- alpha -lipoic acid or (-)- alpha -lipoic acid. |
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R = H or 1-3C alkyl; X<->, Y<-> = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is the use of (III) for the synthesis of racemic 6,8-dimercaptooctanoic acid, (+)-6,8-dihydrolipoic acid, (-)-6,8-dihydrolipoic acid, racemic alpha -lipoic acid, (+)- alpha -lipoic acid or (-)- alpha -lipoic acid.]]></description><edition>7</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011231&DB=EPODOC&CC=GR&NR=3036585T3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011231&DB=EPODOC&CC=GR&NR=3036585T3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BEISSWENGER, THOMAS</creatorcontrib><creatorcontrib>GEWALD, RAINER</creatorcontrib><creatorcontrib>RAUTENBERG, STEPHAN</creatorcontrib><creatorcontrib>OLBRICH, ALFRED DR</creatorcontrib><creatorcontrib>KLENK, HERBERT</creatorcontrib><creatorcontrib>BETHGE, HORST</creatorcontrib><creatorcontrib>HUTHMACHER, KLAUS</creatorcontrib><creatorcontrib>HUEBNER, FRANK</creatorcontrib><creatorcontrib>MOELLER, ROLAND</creatorcontrib><creatorcontrib>SATOR, GERHARD</creatorcontrib><title>Preparation and use of salts of 6,8-bis(amidiniumthio)octanoic acid</title><description><![CDATA[6,8-Bis(amidiniumthio)octanoic acid salts for formula CH2(SC(NH2)2<+>X<->)-CH2-CH(SC(NH2)2<+>Y<->)-CH 2-CH2-CH2-CH2-COOR (III) are new. R = H or 1-3C alkyl; X<->, Y<-> = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is the use of (III) for the synthesis of racemic 6,8-dimercaptooctanoic acid, (+)-6,8-dihydrolipoic acid, (-)-6,8-dihydrolipoic acid, racemic alpha -lipoic acid, (+)- alpha -lipoic acid or (-)- alpha -lipoic acid.]]></description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAOKEotSCxKLMnMz1NIzEtRKC1OVchPUyhOzCkpBjHMdCx0kzKLNRJzM1My8zJLc0syMvM185NLEvPyM5MVEpMzU3gYWNMSc4pTeaE0N4Oim2uIs4duakF-fGpxQWJyal5qSbx7kLGBsZmphWlIiLExMWoAFqMyCA</recordid><startdate>20011231</startdate><enddate>20011231</enddate><creator>BEISSWENGER, THOMAS</creator><creator>GEWALD, RAINER</creator><creator>RAUTENBERG, STEPHAN</creator><creator>OLBRICH, ALFRED DR</creator><creator>KLENK, HERBERT</creator><creator>BETHGE, HORST</creator><creator>HUTHMACHER, KLAUS</creator><creator>HUEBNER, FRANK</creator><creator>MOELLER, ROLAND</creator><creator>SATOR, GERHARD</creator><scope>EVB</scope></search><sort><creationdate>20011231</creationdate><title>Preparation and use of salts of 6,8-bis(amidiniumthio)octanoic acid</title><author>BEISSWENGER, THOMAS ; GEWALD, RAINER ; RAUTENBERG, STEPHAN ; OLBRICH, ALFRED DR ; KLENK, HERBERT ; BETHGE, HORST ; HUTHMACHER, KLAUS ; HUEBNER, FRANK ; MOELLER, ROLAND ; SATOR, GERHARD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_GR3036585TT33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2001</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>BEISSWENGER, THOMAS</creatorcontrib><creatorcontrib>GEWALD, RAINER</creatorcontrib><creatorcontrib>RAUTENBERG, STEPHAN</creatorcontrib><creatorcontrib>OLBRICH, ALFRED DR</creatorcontrib><creatorcontrib>KLENK, HERBERT</creatorcontrib><creatorcontrib>BETHGE, HORST</creatorcontrib><creatorcontrib>HUTHMACHER, KLAUS</creatorcontrib><creatorcontrib>HUEBNER, FRANK</creatorcontrib><creatorcontrib>MOELLER, ROLAND</creatorcontrib><creatorcontrib>SATOR, GERHARD</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BEISSWENGER, THOMAS</au><au>GEWALD, RAINER</au><au>RAUTENBERG, STEPHAN</au><au>OLBRICH, ALFRED DR</au><au>KLENK, HERBERT</au><au>BETHGE, HORST</au><au>HUTHMACHER, KLAUS</au><au>HUEBNER, FRANK</au><au>MOELLER, ROLAND</au><au>SATOR, GERHARD</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation and use of salts of 6,8-bis(amidiniumthio)octanoic acid</title><date>2001-12-31</date><risdate>2001</risdate><abstract><![CDATA[6,8-Bis(amidiniumthio)octanoic acid salts for formula CH2(SC(NH2)2<+>X<->)-CH2-CH(SC(NH2)2<+>Y<->)-CH 2-CH2-CH2-CH2-COOR (III) are new. R = H or 1-3C alkyl; X<->, Y<-> = anions of a mineral acid, alkyl- or arylsulphonic acid, or carboxylic acid. Also claimed is the use of (III) for the synthesis of racemic 6,8-dimercaptooctanoic acid, (+)-6,8-dihydrolipoic acid, (-)-6,8-dihydrolipoic acid, racemic alpha -lipoic acid, (+)- alpha -lipoic acid or (-)- alpha -lipoic acid.]]></abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Preparation and use of salts of 6,8-bis(amidiniumthio)octanoic acid |
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