Oligoribonucleotide- and ribozyme-analoguer with terminal 3',3'- and 5',5'-bonds respectively

The invention relates to oligoribonucleotide analogues with terminal 3'-3' or 5'-5' internucleotide linkages. This modification stabilises the molecules modified in this way, including ribozymes, without adversely changing their properties, including catalytic activities where ap...

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Bibliographische Detailangaben
Hauptverfasser: ROESCH, RUDI, SELIGER, H., DR, ORTIGAO, FLAVIO RAMALHO, KRIST, BERND, ROESCH, HANNELORE
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to oligoribonucleotide analogues with terminal 3'-3' or 5'-5' internucleotide linkages. This modification stabilises the molecules modified in this way, including ribozymes, without adversely changing their properties, including catalytic activities where appropriate.