Transdermal composition containing selegiline

The invention concerns an anhydrous transdermal preparation comprising in a 20-100% lyotropic liquid crystalline arrangement: 5-15 w.% of optically active or racemic N-methyl-N-(phenyl-2-propyl)-2-propynylamine or N-methyl-N-(1-(4-fluoro-phenyl)-2-propyl)-2-propynylamine or their therapeutically acc...

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Bibliographische Detailangaben
Hauptverfasser: PINTER, JANOS, LENGYEL, JOZSEF, SZEGOE, ANDRAS, SZABO, GABRIELLA, SZUETS, TAMAS, SZEKELY, ANNA, MARMAROSI, KATALIN, SZABO, ANNA, TOTH, ANTAL, MAGYAR, KALMAN
Format: Patent
Sprache:eng
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Zusammenfassung:The invention concerns an anhydrous transdermal preparation comprising in a 20-100% lyotropic liquid crystalline arrangement: 5-15 w.% of optically active or racemic N-methyl-N-(phenyl-2-propyl)-2-propynylamine or N-methyl-N-(1-(4-fluoro-phenyl)-2-propyl)-2-propynylamine or their therapeutically acceptable salts, 40-70 w.% of liquid polyoxyethyleneglycol, 10-20 w.% of solid polyoxyethyleneglycol, 2-30 w.% of a nonionic surface active agent, 2-20 w.% of propyleneglycol, if desired 0.5-2 w.% of a polymer the a value of which is > 0.6, and if desired other auxiliary agents.