Process for selectively mono-ortho-hydroxy alkylation of 4-substituted pyridine derivatives

A process is described for the preparation of a pyridine derivative according to the general formula II. For this purpose, a nucleophilic hydroxyalkylation reaction is carried out on the protonated pyridine derivative according to the general formula I under the action of peroxodisulphate.

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1. Verfasser: SCHARBERT, BERND
Format: Patent
Sprache:eng
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Zusammenfassung:A process is described for the preparation of a pyridine derivative according to the general formula II. For this purpose, a nucleophilic hydroxyalkylation reaction is carried out on the protonated pyridine derivative according to the general formula I under the action of peroxodisulphate.