SALT OF DICLOFENAC WITH A CYCLIC ORGANIC BASE AND PHARMACEUTICAL COMPOSITIONS WHICH CONTAIN IT

SALT OF DICLOFENAC WITH A CYCLIC ORGANIC BASE AND PHARMACEUTICAL COMPOSITIONS WHICH CONTAIN IT

The salt of diclofenac with a cyclic organic base is prepared by dissolving diclofenac in a suitable organic solvent, adding said cyclic organic base, reacting the two components together, removing the solvent and crystallising the product obtained. Said salt is water soluble to an extent from 20% w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZIGGIOTTI, ANTONIO, DI SCHIENA, MICHELE
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The salt of diclofenac with a cyclic organic base is prepared by dissolving diclofenac in a suitable organic solvent, adding said cyclic organic base, reacting the two components together, removing the solvent and crystallising the product obtained. Said salt is water soluble to an extent from 20% w/v to an extent exceeding 50% w/v, and is used to prepare pharmaceutical compositions preferably in granular form for use by dissolving in water for oral administration.