3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS

Present invention relates to 3,6-diamino-pyrida-zin-3-yl derivatives of formula (I), (I) pharmaceutical compositions containing them, and their usage as pro-apoptotic agents, as inhibitors of Bcl-xL protein activity. s

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Bibliographische Detailangaben
Hauptverfasser: MARAGNO, Ana Leticia, COLLAN, Frédéric, TIMÁRI, Mátyás Pál, MURRAY, James Brooke, CHANRION, Maïa, STARCK, Jerome-Benoit, STROFEK, Ágnes, DAVIDSON, James Edward Paul, MOLNÁR, Márk, NYERGES, Miklos, DUNKEL, Petra, HERNER, András, RUDASOVÁ, Monika, DODSWORTH, Mark Philip, BEDFORD, Simon, DESOS, Patrice, NOVÁK, Tibor, PACZAL, Attila, KOTSCHY, András, SZIGETI, Marianna, MADARÁSZ, Zoltán, PARSONS, Rachel Jane, WEBB, Paul
Format: Patent
Sprache:eng
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Zusammenfassung:Present invention relates to 3,6-diamino-pyrida-zin-3-yl derivatives of formula (I), (I) pharmaceutical compositions containing them, and their usage as pro-apoptotic agents, as inhibitors of Bcl-xL protein activity. s