3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

An invention relates to 3-pyrimidin-4-yl-oxa¬zolidin-2-ones compounds of formula (I), (I) pharmaceutically acceptable salts, compositions containing them, and usage therefor neomor¬phically active mutant IDH-proteins inhabitation at cancer treatment.

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Bibliographische Detailangaben
Hauptverfasser: SENDZIK, Martin, MANNING, James R, WANG, Yaping, CHO, Young Shin, LEVELL, Julian Roy, CHEN, Zhuoliang, CAFERRO, Thomas Raymond, COSTALES, Abran Q, SUTTON, James, SHAFER, Cynthia, ZHAO, Qian, LIU, Gang, SHULTZ, Michael David
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:An invention relates to 3-pyrimidin-4-yl-oxa¬zolidin-2-ones compounds of formula (I), (I) pharmaceutically acceptable salts, compositions containing them, and usage therefor neomor¬phically active mutant IDH-proteins inhabitation at cancer treatment.