COMPOUNDS AND COMPOSITIONS AS TRK INHIBITORS

Present invention relates to pyrazole[1,5-a] pyrimidines of common formula (I), pharmaceutical compositions containing thereof and application thereat the treatment or prevention of diseases or disorders related to anomalous or deregulated activation of TRK-kinase.

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Bibliographische Detailangaben
Hauptverfasser:	LOREN, JON, FLATT, BRENTON T, FAN, YI, SMITH, JEFFREY M, MOLTENI, VALENTINA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	Present invention relates to pyrazole[1,5-a] pyrimidines of common formula (I), pharmaceutical compositions containing thereof and application thereat the treatment or prevention of diseases or disorders related to anomalous or deregulated activation of TRK-kinase.