Non-Peptide GnRH Agents, Methods For Their Preparation and Use Thereof

1. Technical Result Increase in efficiency of biodistribution in an organism. 2. Essence A composition of the formula or its pharmaceutically acceptable salts, multimers: prodrugs or active metabolites and compound of the formula (1) (wherein R1 - R9, X and het have the value indicated in the descri...

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Hauptverfasser:	TOMPKINS, EILEEN, VALENZUELA, PADERES, GENEVIEVE, DEGUZMAN, HONG, YUFENG, CHRISTIE, LANCE, CHRISTOPHER, PATHAK, VED, P, VAZIR, HARESH, N, FAUST, JAMES, LUTHIN, DAVID, ROBERT, LI, HAITAO, ANDERSON, MARK, BRIAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	1. Technical Result Increase in efficiency of biodistribution in an organism. 2. Essence A composition of the formula or its pharmaceutically acceptable salts, multimers: prodrugs or active metabolites and compound of the formula (1) (wherein R1 - R9, X and het have the value indicated in the description), pharmaceutical composition containing the same and use thereof to obtain the medicament for regulation of gonadotropin secretion with mammalians. 3. Field of Application Medicine.