Thienodibenzoazulene Compounds as Tumor Necrosis Factor Inhibitors

1. Technical Result Increase in efficiency of treatment of diseases caused by excessively secreted tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1). 2. Essence A compound of the formula wherein R1-R10 and X have the values indicated in the specification; said compounds are useful fo...

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Hauptverfasser:	PESIC, DIJANA, HRVACIC, BOSKA, MESIC, MILAN, MERCEP, MLANDEN, ZUPANOVIC, ZELJKO
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	1. Technical Result Increase in efficiency of treatment of diseases caused by excessively secreted tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1). 2. Essence A compound of the formula wherein R1-R10 and X have the values indicated in the specification; said compounds are useful for treatment of all diseases and conditions in mammals, which are caused by excessive secretion factor alpha (TNF-alpha) and interleukine 1 (IL-1); the compounds also demonstrate an analgetic action and can be used to relieve pain; methods for their production and pharmaceutical compositions containing the same. 3. Field of Application Medicine.