New amides of isoindolinyl-2-acetic acid

The invention comprises compounds of formula wherein R is a hydrogen atom or a primary amino-group and R1 and R11, which may be the same or different, are hydrogen atoms or alkyl radicals or are joined directly or through a hetero-atom to form a heterocyclic ring, acid addition salts thereof with p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TONJES HEINZ, SCHMIDT JOACHIM, SCHUHMANN ANDREAS
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention comprises compounds of formula wherein R is a hydrogen atom or a primary amino-group and R1 and R11, which may be the same or different, are hydrogen atoms or alkyl radicals or are joined directly or through a hetero-atom to form a heterocyclic ring, acid addition salts thereof with physiologically acceptable acids, and their preparation by reaction of isoindoline or 5-amino-isoindoline with the appropriate halo-acetic acid amide in a solvent. The compounds of the invention have analgesic activity.