A new and improved cyclopentanopolyhydrophenanthrene derivative and methods for its production

The invention comprises testerone b -phenylpropionate and the preparation thereof by reacting testerone with b -phenylpropionic acid halide in the presence of an organic acid acceptor or with b -phenylpropionic anhydride. A suitable acid acceptor is pyridine which may be mixed with benzene. The reac...

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Bibliographische Detailangaben
1. Verfasser: HEWETT COLIN LESLIE
Format: Patent
Sprache:eng
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Zusammenfassung:The invention comprises testerone b -phenylpropionate and the preparation thereof by reacting testerone with b -phenylpropionic acid halide in the presence of an organic acid acceptor or with b -phenylpropionic anhydride. A suitable acid acceptor is pyridine which may be mixed with benzene. The reaction with the acid anhydride may be carried out at a temperature of the order of 100 DEG C., preferably in the presence of an inert solvent such as pyridine or benzene. A number of detailed examples are given.ALSO:A hormone preparation comprises a solution of testerone b -phenylpropionate in sesame oil or ethyl oleate.