High performance fluorescence imaging module for genomic testing assay

A method for nucleic acid analysis, comprises; providing a flow cell comprising first and second opposing interior surfaces, the first surface having a first plurality of nucleic acid molecules coupled thereto and the second surface having a second plurality of nucleic acid molecules coupled thereto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Michael Previte, Derek Fuller, Chunhong Zhou, Steven Xiangling Chen, Minghao Guo
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CALCULATING CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPUTING CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES COUNTING ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method for nucleic acid analysis, comprises; providing a flow cell comprising first and second opposing interior surfaces, the first surface having a first plurality of nucleic acid molecules coupled thereto and the second surface having a second plurality of nucleic acid molecules coupled thereto, the nucleic acid molecules comprising an optically detectable nucleotide; wherein the first or second interior surfaces are in optical communication with an optical sensor as part of an optical system having a numerical aperture (NA) of less than 0.6 and a field of view (FOV) of greater than 2.5 mm2; and detecting an optical signal from said optically detectable nucleotide of said nucleic acid molecule with said optical sensor.