DSB operation with excluded region

Techniques are disclosed relating to data synchronization barrier operations. A system includes a first processor that may receive a data barrier operation request from a second processor include in the system. Based on receiving that data barrier operation request from the second processor, the first processor may ensure that outstanding load/store operations executed by the first processor that are directed to addresses outside of an exclusion region have been completed. The first processor may respond to the second processor that the data barrier operation request is complete at the first processor, even in the case that one or more load/store operations that are directed to addresses within the exclusion region are outstanding and not complete when the first processor responds that the data barrier operation request is complete.