Formulations of anti-viral compounds

A pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein X is selected from a hydroxyl, a metal salt hydroxylate, an O-linked phosphoester, an O-linked phosphoramidite, an O-linked ester, an O-linked carbamate, an S-linked phosphothioat...

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Bibliographische Detailangaben
Hauptverfasser: Leann J Valentino, Susen Bandyopadhyay, Meghan M Rodriguez, Gurpartap Singh, Rebanta Bandyopadhyay
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein X is selected from a hydroxyl, a metal salt hydroxylate, an O-linked phosphoester, an O-linked phosphoramidite, an O-linked ester, an O-linked carbamate, an S-linked phosphothioate, or an N-linked phosphoramidite, and at least one pharmaceutically acceptable excipient selected from a cysteine compound, an amino acid, an N-acetyl amino acid, an acid or a salt thereof, or any combination thereof. The pharmaceutical composition can be used for the effective treatment of viral infections in humans and other animal species caused by viruses, in particular, RNA viruses and can be administered orally or parenterally.