Preparation and use of pyrazole compound containing 1-(3,4-dimethoxyphenyl)-#-carboline unit

Preparation and use of pyrazole compound containing 1-(3,4-dimethoxyphenyl)-#-carboline unit

The present invention relates to the preparation and a use of a pyrazole compound containing a 1-(3,4-Dimethoxyphenyl)-β-carboline unit. The compound is obtained by means of reacting pyrazole aldehyde with 1-(3,4-dimethoxyphenyl)-β-carboline acyl hydrazine. The pyrazole compound containing a 1-(3,4-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heyi Miao, Yan Zhang, Beibei Zhou, Yong Ling, Hong Dai, Yang Wang, Cheng Qian, Dandan Zheng, Haijun Zhang, Meiling Huang
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to the preparation and a use of a pyrazole compound containing a 1-(3,4-Dimethoxyphenyl)-β-carboline unit. The compound is obtained by means of reacting pyrazole aldehyde with 1-(3,4-dimethoxyphenyl)-β-carboline acyl hydrazine. The pyrazole compound containing a 1-(3,4-Dimethoxyphenyl)-β-carboline unit has good inhibitory activity against HGC-27 tumor cells, and said compound can be used to prepare an anti-tumor cell drug.